advanced in-vivo magnetic resonance spectroscopy


johns hopkins

baltimore, md

The specfitlab is part of the Division of MR Research in the Russell H. Morgan Department of Radiology and Radiological Science at Johns Hopkins University School of Medicine, and the F.M. Kirby Research Center for Functional Brain Imaging at Kennedy Krieger Institute. We work on new in-vivo magnetic resonance spectroscopy data acquisition and analysis techniques that we use to study the biochemistry of the human brain with a clinical MRI scanner.

Learn more about our research, our group members and our collaborators, or check out our latest publications.

If you would like to participate as a volunteer in one of our studies, please find all information here.


Mar 31, 2024 We’re very excited to share Dunja Simicic’s pre-print on using 2D linear-combination modeling to directly integrate frequency-and-phase correction of individual transients. This exciting work is the first application of our new, completely overhauled Osprey modeling module first described in Helge’s (also brand-new at Magn Reson Med) paper. Very cool times ahead.
Mar 05, 2024 Helge has been promoted to Instructor of Radiology and Radiological Science!
Aug 31, 2023 Dr. Helge Zöllner has been awarded a highly prestigious and lucrative K99 Career Development Award from the National Institute on Aging entitled “Brain metabolism across the lifespan using multi-parametric MRS”. This is an outstanding reward for his ever-growing contributions and a fantastic opportunity. Congratulations, Helge!
Jul 14, 2023 Our paper on a continuous automated MRS data analysis workflow is now out - well done Helge!
Jun 14, 2023 Welcome to our new group member, postdoctoral fellow Dunja Simicic who joins us from EPFL in Lausanne!

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